MadSci Network: Biochemistry |
My dentist gave me some Sensodyne-type toothpaste to help reduce tooth sensitivity. It contains 5% potassium nitrate (KNO3), which is also called saltpeter. The toothpaste's web site doesn't give a straight answer as to how it actually works. The two explanations I've found on the web seem to be: 1. it decreases nerve activity (presumably by acting on the neurons themselves) 2. it forms a physically protective barrier to prevent fluid movement that would otherwise activate pain nerves. So my questions are: A. What's the true explanation? B. Why is it okay to put this on my teeth, when saltpeter has some fairly nasty other applications (gunpowder, etc.) C. Various web pages mention hazards of ingesting saltpeter (gastroenteritis, kidney disease, etc)--at what dose should I be concerned? 5% of 1 gram per use, even though one tries to spit it out, might add up. Thanks, Andrew
Re: How does potassium nitrate in Sensodyne toothpaste reduce tooth sensitivity
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