MadSci Network: Cell Biology |
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Costello (1961) reviewed the early history of centriolar studies, and was left confused, to say the least. Gunter Albrecht-Buehler has done much experimental work on centrioles, and proposes that they play a role in sensing the cell's external environment (check here). On the other hand, the orientation of centrioles can be influenced by external factors (check here). The reason that the "function" of the perpendicular orientation has been difficult to define scientifically is that it is not clear how to disrupt this orientation, and watch cell or organismic behavior. Without such experiments, we are left to speculate - we just can't say for sure what the orientation of centrioles "means". |
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