MadSci Network: Medicine |
Shannon, sorry this reply took so long... When we talk about blood pressure from a physical point of view we use the equation F=P/R, where F is Flow rate, P is pressure, and R is resistance. Flow rate can be changed by modulating cardiac output (how much blood is pumped by the heart per minute; resistance can be changed by two things: changing the viscosity of the blood and changing the diameter of the blood vessels the blood flows through. The narrower the blood vessel, the more resistance. As you exercise, your cardiac output increases by virtue of an increased heart rate and the Frank-Starling mechanism (where, when there is more flow into the heart, the heart pumps more strongly in order to get all of the blood out). This greatly increases flow. Since flow is increasing, you would expect pressure to increase as well (F=P/R). This flow increase causes changes in the blood vessels. In order to relieve excessive blood pressure without sacrificing flow, the smooth muscle in the blood vessels relaxes, causing the expansion of the blood vessels. This is called vasodilation. The vasodilation is mediated by the autonomic nervous system. It is important to note that not all vessels become dilated. When you exercise, you typically dilate blood vessels leading to those muscles that are being worked as well as those that supply the brain and heart. The vessels leading to the digestive system, by comparison, tend to constrict to help shunt blood towards the places where it's most needed. In any case, the reason that diastolic blood pressure falls during exercise is that the vasodilation seems proportionate to the systolic pressure (which is much higher than the diastolic) because it represents the greatest danger of stroke, aneurysm, or hemorrhage. The diastolic pressure is the lowest pressure, and if the vessel that you are measuring pressure on is significantly dilated, your diastolic blood pressure will drop despite the increase in cardiac output. Hope this helps. Feel free to ask if you have any more questions. :) Noah Raizman
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