MadSci Network: Chemistry
Query:

Re: How could I make powder into a solid pill form?

Date: Fri Nov 5 13:05:15 1999
Posted By: Joseph Weeks, President, Thermal Products, Inc.
Area of science: Chemistry
ID: 941731453.Ch
Message:

I don't know anything specifically about lightning gel or slush, so I am 
attempting to give you a couple of general guidelines for turning powders 
into pill form.  Generally powders are turned into solid pills by any of 
the following techniques:
1.  The powder is pressed in a closed die under enough pressure to make the 
powder grains hold together,
2.  The powder is mixed with a second powder which is compressible and 
again pressed in a die at high pressure so that everything is held 
together,
3.  The powder is encapsulated in something like a geletin capsule, or
4.  The powder is mixed with a small amount of liquid to form a paste and 
then formed into a pill shape and then allowed to dry.  The liquid helps 
the powder particles join together.
When placed in a liquid, the pills dissolve from the outside, which is 
usually in keeping with the intended use of the pill.

In your application, however, the lightning gel or slush is intended to be 
able to adsorb a large quantity of water and turn it into a "solid" or 
actually a gel.  Polymers which are able to adsorb a large amount of liquid 
are useful as thickening agents or in disposable diapers where they 
decrease the chance of accidental spills.  These type of polymers seem to 
work best when the powder particles are separated far apart from each other 
when exposed to liquid.  When you make gravy, you mix flour into cold water 
before adding it to the hot water and drippings.  If you attempt to add 
"pills" of flour to the hot water, you end up with lumps.

So, in this application, your best approach might be to mix the dry powder 
with a second powder (as much of the second powder as you can get away with 
to keep the gel particles apart), and then press the mixture in a closed 
die to form pills.  Usually the pills would be compressed using at least 
several hundred pounds per square inch pressure.  Good luck!




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